Hydroxypropyl Cellulose (HPC)
Introduction
Registration No.: F20200000504
Hydroxypropyl cellulose (HPC) is a non-ionic semi-synthetic cellulose derivative, appearing as white or off-white granules or powder. It is a commonly used food additive and pharmaceutical excipient.
1. Excellent Solubility: Easily dissolves in polar solvents such as water and ethanol.
2. Unique Thermosensitivity: Precipitates at 40-45℃ and redissolves upon cooling.
3. pH Stability: Maintains stable performance within a pH range of 5.0-8.5.
4. Physical Properties: Exhibits good film-forming ability and notable thermoplasticity.
Advantages
Core applications in the pharmaceutical field:
1. Sustained-Release Formulations: High-viscosity HPC forms a hydration film to precisely control drug release rates.
2. Tablet Processing: Low-viscosity HPC significantly improves particle compressibility, reducing tablet cracking and capping.
3. Coating Material: Excellent film-forming performance with minimal coating defects.
Comprehensive performance advantages:
1. Strong Process Adaptability: Suitable for various processing techniques, including hot-melt extrusion.
2. Safety and Reliability: Non-toxic and non-irritating, certified for pharmaceutical and food-grade use.
3. Multifunctionality: Combines thickening, emulsifying, and suspension-aiding properties.
HPC is an ideal multifunctional excipient for the pharmaceutical, food, and cosmetics industries. It plays an irreplaceable role in improving formulation performance and optimizing production processes, particularly recommended for sustained-release drug development and brittle tablet enhancement.
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